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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Choline and Imipramine

supplement:

Choline

Research Papers that Mention the Interaction

Several commonly prescribed pharmaceuticals known to cross the placental barrier including imipramine , verapamil, propranolol, quinine, flurazepam, amiloride and ritodrin were observed to inhibit conductive choline uptake suggesting an interaction with the mechanism mediating conductive choline transport.
Biochimica et biophysica acta  •  1994  |  View Paper
In slices of the granular layer also a slight Na+-dependence was observed for both serotonin and choline uptake; imipramine and hemicholinium partially inhibited the uptake of serotonin and choline , respectively.
Brain Research  •  1987  |  View Paper
Imipramine and thioridazine (moderately potent anticholinergics) increased the uptake of choline only in the striatum.
Neuropharmacology  •  1983  |  View Paper
The high-affinity uptake of choline by rat cerebral cortical slices was inhibited by high concentrations (10-100 microM) of the tricyclic antidepressant drugs imipramine , desipramine, and iprindole in vitro.
Canadian journal of physiology and pharmacology  •  1981  |  View Paper