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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“The concentration of halothane resulting in half-maximum inhibition of total choline uptake was 1.5%.”
Volatile Anesthetic Agents Inhibit Choline Uptake into Rat Synaptosomes“ Halothane (3% in air, vol/vol) caused a “competitive-like” inhibition of choline uptake in synaptosomes but had no effect on the enzymatic activity of choline acetyl-transferase(ChAT).”
“It is suggested that halothane inhibits ACh synthesis by directly interfering with the carrier-mediated transport system of choline.”
“In cats under halothane or methoxyflurane, iontophoretic applications of choline are only eight times weaker than applications of acetylcholine in evoking firing of neurons in the sensorimotor region of the cerebral cortex.”
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