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Possible Interaction: Choline and Guanidines

supplement:

Choline

supplement:

Guanidines

Research Papers that Mention the Interaction

Five mm unlabelled choline, hemicolinium-3 and guanidine , but not tetraethylammonium, inhibited the cellular uptake of 100 µm choline in LS180 cells.
Biopharmaceutics & drug disposition  •  2014  |  View Paper
Even though choline inhibited guanidine uptake it appeared to reverse this inhibition of virus replication primarily by blocking the intracellular action of guanidine.
The Journal of general virology  •  1987  |  View Paper
However, certain low concentrations of choline and methionine were also able to partially prevent guanidine inactivation.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1969  |  View Paper
Abstract Simple methylated and ethylated compounds (trimethylamine, tetramethylammonium …, methylformate, methylacetate, methanol, triethylamine, tetraethylammonium iodide, choline , hemicholinium HC-3, methionine, ethionine, etc.) … able to inhibit the influence of guanidine on in vitro poliovirus replication either when guanidine acts as a … inhibitor, or when it acts as a growth-promoting factor.
Virology  •  1966  |  View Paper
Abstract The inhibitory effect of guanidine on the multiplication of poliovirus in HeLa cells is suppressed by the amino acids methionine, leucine, and valine but also by choline.
Virology  •  1966  |  View Paper
Choline uptake in the cells was inhibited by unlabeled choline and hemicholinium-3 as well as various organic cations including guanidine , amiloride and acetylcholine.
Placenta  •  2009  |  View Paper
Abstract The ability of choline to block the inhibitory action of guanidine on poliovirus type 2 multiplication was studied in three cell types.
Choline , dimethylethanolamine, and methionine all suppress the growth-supportin activity of 0.4 m M guanidine on a guanidine-dependent strain of poliovirus type 1.
Kinetic studies in all three cell types showed that 10 m M choline rapidly reversed the inhibitory effects of 0.4 m M guanidine.
Virology  •  1971  |  View Paper