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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Choline and glycine are inter-related through their roles in methyl metabolism.”
Relationship of dimethylglycine, choline, and betaine with oxoproline in plasma of pregnant women and their newborn infants.“Glycine, L-alanine, L-serine, L-leucine, L-aspartate, and L-arginine were effective inhibitors and a maximum of 22% inhibition of choline uptake was obtained with 5 mM glycine.”
Effects of amino acids and ethanolamine on choline uptake and phosphatidylcholine biosynthesis in baby hamster kidney-21 cells.“We postulate that choline and glycine are transported by separate mechanisms, and that glycine may play a regulatory role in the control of choline uptake by the hamster heart.”
“Abstract Infusion into rabbits of glycine increased the concentration of plasma choline while infusion of neutralized isovaleric acid which conjugates glycine caused decreased levels.”
“They also noted that glycine, choline, and betaine further reduced the level of liver fat in rats … 9 per cent casein diets that contained additional threonine and that combinations of 1.5 per cent glycine with betaine, …, or choline caused greater reductions than did ….5 per cent glycine alone.”
“ Glycine arising from such choline by the latter mechanisms would exhibit greater dilution with respect to N15 than to U4, whereas in glycine formed via demethylation of betaine, both isotopes would be equally diluted.”
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