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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Choline
Research Papers that Mention the Interaction
“The administration of alpha-GPC was associated with a rapid rise in plasma choline , peak levels being usually observed at the first (0.25 h) or second (0.5 h) sampling time after the injection.”
A comparative study of free plasma choline levels following intramuscular administration of L-alpha-glycerylphosphorylcholine and citicoline in normal volunteers.“While the tCho concentration did not change following doxorubicin treatment, GPC significantly increased and PC decreased.”
“In 9 of the 11 quantified cases the sum of GPC and Cho exceeded 42 % of the total choline-metabolite peak area.”
“ Choline alfoscerate is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue.”
“Treatment with choline alfoscerate , a precursor in the biosynthesis of brain phospholipids which increases bioavailability of choline in the nervous tissue, noticeably reduced the loss of Purkinje and granule neurons in rats of 24 months.”
Age-related structural changes in the rat cerebellar cortex: Effect of choline alfoscerate treatment“Enhanced glycerophosphocholine production also correlated with improved growth in media containing 1.6 M NaCl and choline.”
Hypersaline stress induces the turnover of phosphatidylcholine and results in the synthesis of the renal osmoprotectant glycerophosphocholine in Saccharomyces cerevisiae.
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