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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Choline and Glucagon

supplement:

Choline

Research Papers that Mention the Interaction

Central choline also increases plasma glucagon by augmenting central nicotinic cholinergic neurotransmission by acting presynaptically.
These data show that choline , CDP-choline or phosphocholine increases plasma glucagon concentrations by increasing peripheral nicotinic and muscarinic cholinergic neurotransmissions.
choline (1.5 micromol) administration also increased plasma glucagon ; the effect was blocked by central pretreatment with a neuronal type nicotinic acetylcholine receptor antagonist, mecamylamine (50 microg; i.c.v.)
injection of 200-600 micromol/kg of choline , CDP-choline or phosphocholine produced a dose-dependent increase in plasma glucagon and choline concentrations.
European journal of pharmacology  •  2008  |  View Paper
Acetyl choline at concentrations of 10 to 100 μM. stimulated release of glucagon both at the low glucose strength as well as at the high concentration, which in itself inhibits basal glucagon release.
Diabetes  •  1973  |  View Paper