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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Choline
drug:
Furosemide
Research Papers that Mention the Interaction
“Bladder accumulation of choline can hide local small volume recurrence: overcome this drawback by the administration of Furosemide.”
[Focus: Prostate cancer and PET-choline].“Substitution of choline or Ca(2+) for K(+) in the external solution or the external application of furosemide caused concomitant decreases in the cytosolic K(+) and Cl(-) activities that were accompanied by a decrease in the water segregation activity of the contractile vacuole complex.”
Osmoregulation in Paramecium: in situ ion gradients permit water to cascade through the cytosol to the contractile vacuole.“All the volume‐activated pathways (K+, Na+, taurine, choline ) are fully inhibited by furosemide and by inhibitors of the anion exchanger such as DIDS and niflumic acid.”
“These two effects were inhibited by furosemide and by the replacement of Na+ by choline and Cl- by SO4(2-) in the bath fluid.”
“Lowering the extracellular sodium concentration, [Na]o, by replacing Na with choline , significantly reduced the effect of furosemide on ai(Cl).”
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