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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Choline and Folic Acid

supplement:

Choline

supplement:

Folic Acid

Research Papers that Mention the Interaction

This is an important question to resolve because choline , if taken periconceptionally, might add to the protective effect currently being achieved by folic acid.
The American journal of clinical nutrition  •  2014  |  View Paper
When treated daily with choline and betaine, pyridoxine, or folic acid , there was a normalization of the postmethionine plasma homocysteine level in 16 of 19 patients.
Arteriosclerosis and thrombosis : a journal of vascular biology  •  1993  |  View Paper
is a more active precursor of methylethanolamine in a choline requiring mutant of Neurospora than is methionine-C14H3, and evidence has been presented suggesting that in rats fed folic acid deficient diets, the synthesis of two of the methyl groups of choline is decreased (14, 15).
The Journal of biological chemistry  •  1960  |  View Paper
Cystine exerts a positive effect … in and vitamin B12 and folic acid … choline and methionine.16 Some evidence suggests that unidentified factors may be present in the protein molecule which affect …, has recently been purified from casein and from certain yeasts which protects rats against dietary necrotic liver degeneration.’?.
Annals of the New York Academy of Sciences  •  1954  |  View Paper