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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Choline and Dopamine

supplement:

Choline

Research Papers that Mention the Interaction

Thus, for example, brain levels of tryptophan, tyrosine, or choline can control the rates at which neurons synthesize serotonin, dopamine , or acetylcholine, respectively.
Metabolism: clinical and experimental  •  2008  |  View Paper
…,choline inhibits the influx of dopamine with an IC50 value of 17 microM and stimulates the efflux of dopamine with a K(m) value of 8.20 microM. These results strongly suggest that dopamine is transported by the choline exchanger previously reported to be present in red blood cells.
Experimental physiology  •  1996  |  View Paper
Compared with control animals, rats administered total parenteral nutrition plus choline for 5 days showed a decrease of approximately 5- and 2-fold in urinary dopamine and norepinephrine concentration, respectively.
Drug metabolism and disposition: the biological fate of chemicals  •  2004  |  View Paper
Dopamine contents were unchanged after exposure to Li+ and Na+, but were reduced by Ch+.
Progress in Neuro-Psychopharmacology and Biological Psychiatry  •  1992  |  View Paper
Abstract Oral administration of either choline or physostigmine to rats stimulated the metabolism of dopamine in brain.
Life sciences  •  1979  |  View Paper