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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Choline
drug:
Desipramine
Research Papers that Mention the Interaction
“The high-affinity uptake of choline by rat cerebral cortical slices was inhibited by high concentrations (10-100 microM) of the tricyclic antidepressant drugs imipramine, desipramine , and iprindole in vitro.”
High-affinity uptake of choline in slices of rat cerebral cortex: effects of antidepressant and anticholinergic drugs.“ Desipramine increases the disorder of the choline site at the phosphatidylcholine headgroup while leaving the conformation and dynamics of the phosphate region largely unchanged.”
Effects of antidepressants on the conformation of phospholipid headgroups studied by solid‐state NMR
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