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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Choline
drug:
Decamethonium
Research Papers that Mention the Interaction
“The triple effects of choline and decamethonium , i. e. (i) weak depolarization, (ii) potentiation of Ach in normal Ringer solution, (iii) inhibition of Ach in the presence of prostigmine, can be explained by competitive reactions between the drugs and receptor as well as Ach-esterase molecules.”
Interaction at end-plate receptors between different choline derivatives“Inactivation by N-ethylmaleimide can be accelerated by external choline and prevented by decamethonium , which acts as an inhibitor of choline entry in infected cells (as with dodecyltrimethylammonium).”
Increased permeability to choline in simian erythrocytes after Plasmodium knowlesi infection.“ Choline and decamethonium concentrations for which the I‐‐V relation was straight produced much greater depression of miniature end‐plate currents than did carbachol concentrations which produced the same membrane current at the holding potential.”
“Stimulation can thus be interpreted as an example of accelerative exchange diffusion, which should mean that efflux of choline or neostigmine accumulated by the slices accelerates decamethonium influx.”
“ Decamethonium (C10) was found to inhibit choline uptake more than hexamethonium (C6).”
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