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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
Research Papers that Mention the Interaction
“ Curcumin … choline (1 mM)‐induced Ca2+ transients with an EC50 value of 133 nM. The potentiating effect of curcumin was not observed in Ca2+ transients induced … presence of Ca2+ channel antagonists nifedipine (1 &mgr;M), verapamil (1 &mgr;M), ω‐conotoxin (1 &mgr;M), and bepridil (10 &mgr;M).”
Curcumin potentiates the function of human α7-nicotinic acetylcholine receptors expressed in SH-EP1 cells“In patch clamp studies, fast inward currents activated by choline , a selective agonist of α7-nAChRs, were significantly potentiated by CUR.”
“Moreover, choline induced enhancement of spontaneous inhibitory postsynaptic currents was markedly increased in the presence of CUR.”
Curcumin Potentiates α7 Nicotinic Acetylcholine Receptors and Alleviates Autistic-Like Social Deficits and Brain Oxidative Stress Status in Mice
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