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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Choline
drug:
Antipsychotic Agents
Research Papers that Mention the Interaction
“RBC choline concentration was significantly lower in patients medicated with neuroleptics and cogentin.”
RBC and plasma choline in neuroleptic-treated schizophrenic patients“Haloperidol, after a single dose, caused a significant increase of high affinity choline uptake (18%) only in the cortex, but repeated administration of the antipsychotic drug produced consistent augmentation of choline uptake in both cortical and striatal synaptosomes.”
Effect of chronic treatment with amitriptyline and haloperidol on high affinity uptake of choline by synaptosomes from various regions of rat brain“It is concluded that the increase in high‐affinity choline uptake caused by chronic administration of neuroleptic drugs is associated with a parallel increase in choline utilization for ACh formation.”
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