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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Choline and Antipsychotic Agents

Research Papers that Mention the Interaction

RBC choline concentration was significantly lower in patients medicated with neuroleptics and cogentin.
Psychiatry Research  •  1989  |  View Paper
Haloperidol, after a single dose, caused a significant increase of high affinity choline uptake (18%) only in the cortex, but repeated administration of the antipsychotic drug produced consistent augmentation of choline uptake in both cortical and striatal synaptosomes.
Neuropharmacology  •  1982  |  View Paper
It is concluded that the increase in high‐affinity choline uptake caused by chronic administration of neuroleptic drugs is associated with a parallel increase in choline utilization for ACh formation.
Journal of neurochemistry  •  1980  |  View Paper