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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cholestyramine Resin
supplement:
Grape Seed Extract
Research Papers that Mention the Interaction
“ CHY also induced hepatic lipogenic gene expression, which was attenuated by co-administration with GSPE.”
“Collectively, this study presents novel evidence demonstrating that GSPE provides additive and complementary efficacy as a lipid-lowering combination therapy in conjunction with CHY by attenuating hepatic cholesterol synthesis, enhancing BA biosynthesis and decreasing lipogenesis, which warrants further investigation.”
“Notably, GSPE decreased intestinal apical sodium-dependent bile acid transporter (Asbt) gene expression, while CHY significantly induced expression.”
“Results reveal that GSPE treatment alone, and co-administration with CHY , regulates BA, cholesterol and TG metabolism differently than CHY administration alone.”
Grape Seed Procyanidins and Cholestyramine Differentially Alter Bile Acid and Cholesterol Homeostatic Gene Expression in Mouse Intestine and Liver
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