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“Both cholestyramine and CCK significantly increased the first phase of glucose (8.4 mM)-stimulated release of insulin [mean insulin output (ng/min): control, 2.0 ± 0.1; cholestyramine, 2.7 ± 0.2; CCK, 2.6 ± 0.23.”
“Since pancreatic insulin content was not affected by cholestyramine and CCK treatment, cholestyramine and CCK may increase the sensitivity of p cells to glucose.”