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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cholestyramine Resin
supplement:
Fat Soluble Vitamin Product
Research Papers that Mention the Interaction
“Large doses of cholestyramine (> 32 g/day) may be associated with malabsorption of fat-soluble vitamins.”
Adverse Effects of Hypolipidaemic Drugs“Finding the adequate dosage is not simple, … many drugs, for example elderly patients, because cholestyramine , and generally all BAS, may … malabsorption of fat and liposoluble vitamins (vitamins A, D and K), increasing the risk of osteoporosis and coagulation … can interact with different types of drugs, thus decreasing their efficacy.”
“This case demonstrates that one should be aware of the possibility of depletion of fat-soluble vitamins during the long-term use of cholestyramine.”
“Cholestyramine therapy has been associated with malabsorption of vitamins; several reports suggest that cholestyramine affects absorption of the fat-soluble vitamins K and D and, in addition, may alter water-soluble vitamins, including folic acid.”
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