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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Cholecystokinin
supplement:
Progesterone
Research Papers that Mention the Interaction
“The high level of sexual steroids also influences cholecystic kinetics: progesterone , in particular, negatively affects the contractile response to cholecystokinin-pancreozymin stimulus.”
[Cholestasis in pregnancy].“ Progesterone also significantly impairs gallbladder emptying in response to cholecystokinin.”
Progesterone alters biliary flow dynamics.“Gallbladder from animals on progesterone exhibited a marked decrease in contractile response to CCK and bethanechol compared with controls (P < 0.05).”
“During metestrus, a period of low estradiol in the presence of progesterone , food intake was also suppressed by CCK (5 and 10 micrograms/kg).”
“Our data suggest that the effect of CCK on food intake in female rats may be dependent on the presence of progesterone.”
“ progesterone pretreatment produced right-ward shifts in the acetylcholine and octapeptide of cholecystokinin curves that were characterized by significant decreases in the maximal contractile response.”
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