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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cholecystokinin
supplement:
Isoleucine
Research Papers that Mention the Interaction
“Our data demonstrated that stimulation of porcine … tissue with 10 mM l-leucine, l-isoleucine or BCAAs mix (l-leucine : l-isoleucine : l-valine = 1 : 0.51 : 0.63) for 2 hours significantly increased mRNA expression and protein abundance of T1R1/T1R3 and secretion of CCK (P < 0.05).”
Branched chain amino acids stimulate gut satiety hormone cholecystokinin secretion through activation of the umami taste receptor T1R1/T1R3 using an in vitro porcine jejunum model.“The secretory response evoked by CCK-PZ was inhibited by other amino acids (Ala, Asp, Asn, Gly, Ile , Leu, Lys, Met, Phe, Pro, Thr, Trp, Val, in each 20 mM).”
“Asparagine, arginine, isoleucine and phenylalanine administered under the stimulation of secretin-pancreozymin significantly inhibited the secretion of pancreatic juice by 23%, 15%, 13% and 13%, and the output of amylase by 53%, 37%, 27% and 18%, respectively.”
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