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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cholecystokinin
supplement:
Epinephrine
Research Papers that Mention the Interaction
“Administration of epinephrine in combination with polyvinylpyrrolidone or cholecystokinin in threshold doses (1/10–1/25 of the minimum effective dose) produced maximum analgesic and antidepressant effects, but did not cause bradycardia.”
Epinephrine potentiates the analgesic and antidepressant effects of polyvinylpyrrolidone and cholecystokinin due to stimulation of afferents in the gastric mucosa“Second, epinephrine blocked the effect of high glucose on both insulin release and potentiation of CCK action.”
“In the functional analysis, an antagonistic interaction between cholecystokinin-8 and adrenaline as well as between cholecystokinin and neuropeptide Y is demonstrated opening up the possibility that cholecystokinin peptides act as intrinsic modulators in the putative cholecystokinin/neuropeptide Y/adrenaline synapses in the nucleus tractus solitarius.”
Intracisternal administration of cholecystokinin-8 counteracts the central cardiovascular effects of adrenaline and NPY. A study based on the coexistence of cholecystokinin, phenylethanolamine N-methyltransferase and neuropeptide Y immunoreactivity in neurons of the nucleus tractus solitarius
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