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Last Updated: 2 years ago

Possible Interaction: Cholecystokinin and Cocaine

supplement:

Cocaine

Research Papers that Mention the Interaction

In vitro, cocaine (2 or 10 mM) did not modify basal release of amylase; at a concentration of 2 mM, it reduced the secretory response to pancreozymin by 32% and that to urecholine by 68%.
The American Journal of Digestive Diseases  •  2005  |  View Paper
Cocaine treatment of cocaine‐sensitized rats increased CCK to 0.98.
Treating drug‐naive rats with cocaine caused a significant increase in CCK to 0.58 pg.
Journal of neurochemistry  •  2002  |  View Paper
A significant increase in striatal CCK mRNA was observed 8 h after a single injection of cocaine (15 mg/kg, i.p.)
Cocaine and benztropine, two dopaminergic agonists known to induce DA release and to block its re-uptake, produced a time dependent increase in CCK mRNA content in rat striatum.
Brain research. Molecular brain research  •  1992  |  View Paper