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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chlorzoxazone
supplement:
Lauric Acid
Research Papers that Mention the Interaction
“The (omega-1)-hydroxylation of lauric acid was inhibited by ethanol (Ki = 3.5 mM), acetone (IC50 = 10 mM) dimethylsulfoxide, chlorzoxazone (competitive inhibitors of CYP2E1), diethyldithiocarbamate, and diallylsulfide (both selective mechanism-based inactivators of CYP2E1).”
Validation of the (omega-1)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1.
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