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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chlorthalidone
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“These drugs … range) some CA isozymes involved in critical physiologic processes, among the 16 … example, metolazone against CA VII, XII, and XIII, chlorthalidone against CA VB, VII, IX, XII, and XIII, indapamide against CA VII, IX, … against CA I, II, and XIV, and bumetanide against CA IX and XII.”
Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct.“Our data show that CTL is associated with greater reduction in 24 h UCa compared to similarly dosed HCTZ.”
“Patients on CTL 25 mg had a greater reduction in UCa (164 mg; 41 %) than those on HCTZ (85 mg; 21 %), p = 0.01.”
“ Chlorthalidone treatment in dogs increased calcium and decreased potassium in plasma (P < .01).”
Effect of chlorthalidone on blood vessels.
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