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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Chlorpropamide and Glucose



Research Papers that Mention the Interaction

We conclude that inhibition of endogenous glucose production during chronic chlorpropamide therapy is an important mechanism for the lowering of FPG and that enhanced insulin secretion is the reason for the major part of this inhibition.
Diabetes  •  1982  |  View Paper
Diabinese monotherapy reduced bilirubin levels, while combined therapy reduced glucose , ALP, AST, and ALT levels more than single therapy.
Journal of experimental pharmacology  •  2010  |  View Paper
Since lipolysis as well as re-esterification of FFA is accelerated by glucose, present data would indicate that chlorpropamide primarily interferes with the glucose metabolism or the stimulatory action of glucose on the two pathways of the triglyceride-FFA cycle.
Acta medica Scandinavica  •  1970  |  View Paper
Only chlorpropamide significantly potentiated glucose induced insulin release.
Biochemical and biophysical research communications  •  1986  |  View Paper
The reductions in phosphorylase a activity after treatment with chlorpropamide were more than sufficient to explain the accompanying decreases in hepatic glucose production.
Endocrinology  •  1985  |  View Paper