Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Chlorpromazine and Ubiquinone



Research Papers that Mention the Interaction

CoQ10 prevented significantly the decrease in VMRT and the disturbance of mitochondrial function induced by CPZ , but did not prevent the hypotensive effect of CPZ.
Journal of electrocardiology  •  1981  |  View Paper
Coincubation of the cultures with CPZ and CoQ led to a dose-dependent increase in ATP contents and beating rates.
Japanese heart journal  •  1984  |  View Paper
In this study, we … treatment with taurine and coenzyme Q10 (COQ-10), compounds with steroidogenic-gonadotropin … attenuate the negative impacts of chlorpromazine on steroidogenic, gonadotropin, thyroid and HPA-axis hormones, dopamine levels, catalepsy behavior and neuronal … and pituitary gland in the preventive and reversal treatments in male Wister rats.
Taurine and COQ-10 reduced the changes in thyroid hormones, corticosterone release, histological distortions of the hypothalamus and the pituitary gland of chlorpromazine-treated rats.
Naunyn-Schmiedeberg's archives of pharmacology  •  2020  |  View Paper