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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Chlorpromazine and Phosphatidylethanolamine

Research Papers that Mention the Interaction

CPZ significantly decreased the ratio of saturated to unsaturated fatty acids, particularly in the PC and PE fractions, while the effect of PPZ was only slight.
Concurrently, CPZ raised microsomal phosphatidylcholine (PC), phosphatidylethanolamine ( PE ), phosphatidylserine-inositol (PSI) and sphingomyelin (SM), while PPZ increased PC and PE, but did not affect the levels of PSI and SM.
The Journal of toxicological sciences  •  1992  |  View Paper
Under these conditions, CPZ inhibited the incorporation of [ 32 P]orthophosphate into phosphatidylcholine and phosphatidylethanolamine and of [U- 14 C]glycerol into phosphatidylcholine and triglycerides, in a dose-dependent manner.
Biochemical pharmacology  •  1981  |  View Paper