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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chlorpromazine
supplement:
Phenylalanine
Research Papers that Mention the Interaction
“The uptake of phenylalanine and 1-… in the same dose range, but CPZ … phenylalanine into acid-insoluble material with 50 per cent inhibition at 6·5 × 10 −5 M. Actinomycin D stimulated … the HE-cells, 5·0 μg/ml increased the uptake to 160 per cent of the controls.”
Effects of chlorpromazine and actinomycin D on uptake and incorporation of certain amino acids, hypoxanthine and thymidine in cultures of human skin epithelial cells.“ Chlorpromazine , calmidazolium, and trifluoperazine inhibited the incorporation of [3H]hypoxanthine and [3H]phenylalanine into Plasmodium falciparum organisms in cultures with 50% inhibitory concentrations varying from 5.1 microM (with calmidazolium) to 48 microM (with chlorpromazine), the former being more sensitive than the latter.”
Effect of calmodulin inhibitors on viability and mitochondrial potential of Plasmodium falciparum in culture
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