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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chlorpromazine
supplement:
Magnesium
Research Papers that Mention the Interaction
“ Chlorpromazine , an antipsychotic agent, which has been shown to block the dopamine-receptor site, totally inhibited the dopamine-stimulated Na + -K + and Mg 2 + ATPase activities in mouse brain synaptosomes.”
Kinetics of catecholamine sensitive Na+-K+ ATPase activity in mouse brain synaptosomes.“It is proposed that chlorpromazine , caffeine or d -amphetamine can evoke catecholamine release by mobilizing different calcium pools within the adrenal medullary chromaffin cell and that magnesium can block this effect.”
“The addition of Mg 2 + to the microsomal drug oxidase experimental suspensions caused an increase in the disappearance of chlorpromazine in both the rat and rabbit.”
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