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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chlorpromazine
supplement:
Glutathione
Research Papers that Mention the Interaction
“The effect on annexin binding and ATP but not on GSH was significantly enhanced in the presence of chlorpromazine (10 microM).”
Stimulation of erythrocyte phosphatidylserine exposure by chlorpromazine.“This method is based on the observation that when added to a pre-formed palladium-thiorpromazine complex which has an absorption maximum at 565 nm, GSH competitively displaces chlorpromazine from the complex, resulting in a decrease in absorbance which is in direct proportion to the quantity of GSH added.”
“ Chlorpromazine showed the greatest effect by increasing the amount of glutathione reduced by about 2-fold at a concentration of 3 m M .”
Effect of chlorpromazine and amytal on the reduction of glutathione.“ Chlorpromazine and promethazine in optimum concentrations do inhibit glutathione- or ascorbate-induced swelling-lysis, late isotonic swelling, and a late or second phase of hypotonie swelling.”
THE EFFECT OF CHLORPROMAZINE, PROMETHAZINE, AND DIPHENHYDRAMINE ON SWELLING OF ISOLATED LIVER MITOCHONDRIA.
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