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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chlorpheniramine
supplement:
Oxytocin
Research Papers that Mention the Interaction
“Also, co-injection of chlorpheniramine plus oxytocin significantly decreased the effect of oxytocin on food intake (P < 0.001).”
Involvement of histaminergic and noradrenergic receptors in the oxytocin-induced food intake in neonatal meat-type chicks“Furthermore, the increases in OT concentration in dialysates and plasma were prevented by simultaneous administration of chlorpheniramine (an H1 receptor antagonist) or ranitidine (an H2 receptor antagonist) as well as by the adrenergic antagonist phentolamine.”
“The contraction of isolated rat and rabbit uteri induced by oxytocin and PGF2 alpha was markedly inhibited by chlorpheniramine (Chl) and astemizolum (Ast), both of which also decreased the resting tension of uteri, and their spontaneous contraction.”
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