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The American journal of physiology • 1979 | View Paper
“The results are consistent with the idea that chlorothiazide enhances the ratio of calcium to sodium reabsorptions and that this tendency for absolute hypocalciuria can be overridden by a large natriuretic response to the drug.”
“Under the influence of chlorothiazide , there was a strong linear correlation between the changes in the excretion of calcium and sodium.”
The New England journal of medicine • 1971 | View Paper
“The fraction of sodium remaining at the distal tubule rose from 4.0 +/- 1.4 to 10.0 +/- 1.4% while that of calcium decreased from 10.2 +/- 1.1 to 7.6 +/- 1.2% following administration of chlorothiazide.”
The American journal of physiology • 1975 | View Paper
“The decrease in clearance of diffusible calcium seen after intravenous chlorothiazide differs from the calciuria observed after the administration of mercurials and acetazolamide.”
“The results demonstrate that intravenous chlorothiazide causes a significant increase in both phosphorus and uric acid clearances and an equivocal decrease in the clearance of diffusible calcium.”