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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chloroquine
supplement:
Tyrosine
Research Papers that Mention the Interaction
“Melanin content in P-MDCK cells depended on the concentration of l-tyrosine in culture medium, and … l-tyrosine content from 0 to 2 mM. When the cells were grown in 2 mM l-tyrosine, … chloroquine was 2.3-fold higher and the … compared to wild type MDCK cells.”
Pigmented-MDCK (P-MDCK) cell line with tunable melanin expression: an in vitro model for the outer blood-retinal barrier.“Presentation of ABA-poly-L-glutamic, alanine, tyrosine (ABA-GAT) is similarly inhibited by chloroquine , but in contrast to ABA-Tyr it is also inhibited by leupeptin.”
An intracellular pathway is required for ABA-tyrosine presentation to T cells.“Furthermore, tyrosine release from BAT during fasting was also reduced by injections of chloroquine or leupeptin, a thiol-protease inhibitor.”
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