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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Chloroquine
supplement:
Quinidine
Research Papers that Mention the Interaction
“The risks of fast intravenous injection of quinine, the striking prolongation of the electrocardiographic (ECG) QT interval triggered by quinidine , and the lethality of CQ in overdose have separately caused substantial concern.”
Chloroquine and hydroxychloroquine for COVID-19: implications for cardiac safety“As reported previously for other HERG blockers (e.g., MK-499, cisapride, terfenadine, chloroquine ), the potency of quinidine was reduced >100-fold by the mutation of key aromatic residues (Y652, F656) located in the S6 domain.”
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