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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chloroquine
supplement:
NADH
Research Papers that Mention the Interaction
“We now report that chloroquine inhibits NADH diferric transferrin reductase as well as the proton release stimulated by diferric transferrin from liver and HeLa cells.”
Transplasma membrane electron and proton transport is inhibited by chloroquine.“ Chloroquine hence competes with NADH for binding to the enzyme, acting as a competitive inhibitor for this critical glycolytic enzyme.”
Chloroquine Binds in the Cofactor Binding Site ofPlasmodium falciparum Lactate Dehydrogenase*“Both chloroquine diphosphate and acetone (96%) treatment irreversibly inhibited NADH but not succinate oxidation.”
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