supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago
drug:
Chloroquine
supplement:
Kaempferol
Research Papers that Mention the Interaction
“Finally, co-treatment with the autophagy inhibitor chloroquine weakened the effects of luteolin on cell apoptosis.”
Luteolin Promotes Cell Apoptosis by Inducing Autophagy in Hepatocellular Carcinoma“Conclusion Together, these results suggest that Luteolin has the capacity to induce selectively apoptotic cell death both in primary cutaneous SCC cells and in metastatic SCC cells in combination with chloroquine , an inhibitor of autophagosomal degradation.”
“Blocking autophagy with chloroquine antagonized the inhibitory effects of Kae on inflammation, suggesting that autophagy might be required in the therapeutic effects of Kae on silicosis.”
Kaempferol Modulates Autophagy and Alleviates Silica-Induced Pulmonary Fibrosis.“This effect of luteolin was also confirmed in vitro, which was reversed by the autophagy inhibitor, chloroquine (CQ).”
Luteolin Exerts Neuroprotection via Modulation of the p62/Keap1/Nrf2 Pathway in Intracerebral Hemorrhage“Moreover, combination treatment of chloroquine and kaempferol also presented significant (P < 0.05) antimalarial effects, although the effects were not significantly different from the chloroquine treated group.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback