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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chloroquine
supplement:
Gossypol
Research Papers that Mention the Interaction
“Moreover, gossypol acts as an autophagy inducer in ATG5 knockout cells while blocking the later stages of the autophagy process in WT cells, which was determined by measuring autophagic flux after co-treatment of gossypol with chloroquine (late-stage autophagy inhibitor).”
Cytoprotective role of autophagy against BH3 mimetic gossypol in ATG5 knockout cells generated by CRISPR-Cas9 endonuclease.“The results showed that the interaction of GP and CQ in LP and NP-fed rats produced significant effects (P<0.001) on the serum levels of cholesterol and triglycerides.”
Reduced level of serum cholesterol in low protein-fed Wistar rats administered gossypol and chloroquine.
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