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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chloroquine
supplement:
Diindolylmethane
Research Papers that Mention the Interaction
“In conclusion, we have confirmed that DIM and 4,4'-Br2DIM are effective agents against prostate cancer in vivo and shown that inhibition of autophagy with CQ enhances the anticancer efficacy of DIM.”
“Moreover, a combination of DIM (10 mg/kg) and CQ (60 mg/kg), 3× per week, significantly decreased PC-3 tumor growth in vivo after 3 and 4 weeks of treatment.”
Autophagy inhibition improves the chemotherapeutic efficacy of cruciferous vegetable-derived diindolymethane in a murine prostate cancer xenograft model“Autophagy inhibitors bafilomycin or chloroquine inhibited DIM induced autophagy.”
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