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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chloroquine
supplement:
Ascorbate
Research Papers that Mention the Interaction
“ Ascorbate was found to decrease parasite susceptibility to chloroquine , suggesting that iron deprivation may be an important factor in the anti-malarial action of QCDs.”
Inhibition by anti-malarial drugs of haemoglobin denaturation and iron release in acidified red blood cell lysates--a possible mechanism of their anti-malarial effect?“It is proposed that sodium ascorbate by virtue of its reducing properties provides some protection to the intralysosomal hydrolases against the inhibitory action of chloroquine.”
“ Chloroquine , a known inhibitor of plasma membrane redox systems, inhibits the ascorbate stabilization, the inhibition being partially reversed by coenzyme Q6.”
Extracellular ascorbate stabilization as a result of transplasma electron transfer inSaccharomyces cerevisiae
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