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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Chloroprocaine and Sodium Bicarbonate

Research Papers that Mention the Interaction

&NA; Increasing the pH of 2% chloroprocaine CP ) with sodium bicarbonate to pH 7.7 hastens the onset of epidural analgesia.
Regional anesthesia  •  1990  |  View Paper
Sodium bicarbonate has been reported to hasten epidural onset of chloroprocaine , lidocaine and bupivacaine while tris(hydroxymethyl) aminomethane (THAM) has been shown to delay the onset of epidurally administered chloroprocaine in parturients.
International journal of obstetric anesthesia  •  1992  |  View Paper