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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chloroprocaine
supplement:
Sodium Bicarbonate
Research Papers that Mention the Interaction
“&NA; Increasing the pH of 2% chloroprocaine CP ) with sodium bicarbonate to pH 7.7 hastens the onset of epidural analgesia.”
Alkalinization of Chloroprocaine for Epidural Anesthesia: Effects of pCO2 at Constant pH“ Sodium bicarbonate has been reported to hasten epidural onset of chloroprocaine , lidocaine and bupivacaine while tris(hydroxymethyl) aminomethane (THAM) has been shown to delay the onset of epidurally administered chloroprocaine in parturients.”
Does the addition of tris(hydroxymethyl) aminomethane to 0.5% bupivacaine delay epidural onset in parturients?
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