Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Chlorogenic Acid and Copper

supplement:

Copper

Research Papers that Mention the Interaction

The exposure to Cu significantly increased the synthesis of phenolic compounds in shoots of plants exposed 21 days to Cu, where 5-caffeoylquinic acid reached the highest concentrations.
Plants  •  2020  |  View Paper
Further, we revealed that 5-caffeoylquinic acid inhibited melanogenesis by chelating a copper cation from a copper–tyrosinase complex.
ACS omega  •  2020  |  View Paper
Interestingly, chlorogenic acid was extremely elevated by the highest Cu dose (21-fold higher than control) suggesting its involvement in antioxidative protection.
Plant Cell Reports  •  2007  |  View Paper
However ortho-diphenols such as catechol, methylcatechol, caffeic acid, chlorogenic acid , and phaselic acid show decreased responses in the presence of copper.
Analytical biochemistry  •  2005  |  View Paper