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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Chlormethiazole and Glycine



Research Papers that Mention the Interaction

These observations suggest that the active steroids and chlormethiazole increase the functional interaction of both glycine and strychnine with the glycine-gated chloride channel.
Neuropharmacology  •  1992  |  View Paper
Applied micro-iontophoretically, chlormethiazole was found to potentiate the inhibitory responses to GABA, muscimol and glycine , but not to acetylcholine.
Acta psychiatrica Scandinavica. Supplementum  •  1986  |  View Paper
Intraperitoneal administration of CMZ (50-600 mumol kg-1) also enhanced responses to microiontophoretically applied GABA, muscimol and glycine.
When applied with lower currents CMZ did not cause changes in firing rate, but enhanced the inhibitory effects of gamma-aminobutyric acid (GABA), muscimol and glycine in a dose-dependent manner.
British journal of pharmacology  •  1983  |  View Paper