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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chlorisondamine
supplement:
Niacin
Research Papers that Mention the Interaction
“ Nicotinic blockade in vivo was attempted with either the classical antagonist chlorisondamine or the novel antagonist catestatin.”
Catecholamine Secretory Vesicle Stimulus-Transcription Coupling in Vivo“ Chlorisondamine , a long-lasting nicotinic acetylcholine receptor antagonist, reverted significantly the nicotinic protective effects on dopamine concentrations.”
“These findings suggest that chlorisondamine blocks nicotinic effects widely within the brain.”
“4 Both in vitro and in vivo administration of chlorisondamine blocked nicotinic responses to acetylcholine (10−4 m).”
“These results support findings from other behavioural procedures indicating that centrally administered chlorisondamine causes a long-term blockade of central nicotinic mechanisms.”
“Treatment with chlorisondamine , which blocks nicotinic ganglionic transmission, also increased SP, reproducing the effects of decentralization.”
“The cholinergic response is nicotinic and blocked by pentolinium, hexamethonium, chlorisondamine and dihydro-beta-erythroidine.”
“produced a small but significant reduction of the pressor response to lumbar electrical stimulation prior and following blockade of nicotinic transmission with chlorisondamine (1.0 mg/kg).”
“Combined nicotinic ganglion blockade by chlorisondamine (1 mg/kg) and muscarinic ganglion blockade by atropine (50mug/kg) abolished the reflex vasomotor response but did not alter hindlimb peripheral resistance.”
“ Nicotinic ganglion blockade by chlorisondamine (1 mg/kg) significantly reduced reflex vasomotor responses but did not significantly alter hindlimb peripheral resistance.”
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