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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Chlorine and Glycine

supplement:

Glycine

Research Papers that Mention the Interaction

Chlorine , and other small electron-withdrawing substituents in the 4- … ring, greatly enhanced binding and selectivity for the glycine site over the glutamate site of the NMDA receptor; one of the most potent compounds is …-3-yl)propionic acid (IC50 = 170 nM; greater than 2100-fold selective for glycine).
Journal of medicinal chemistry  •  1992  |  View Paper
The data reveals that while fluorine and chlorine have strong tendencies favoring interactions with the backbone Lewis bases at glycine , the trend is not restricted to the achiral amino acid backbone for larger halogens.
J. Chem. Inf. Model.  •  2013  |  View Paper