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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Chlorhexidine and Resveratrol

supplement:

Resveratrol

Research Papers that Mention the Interaction

Expression of adeB was significantly reduced in the combination of resveratrol with chlorhexidine indicating that resveratrol inhibits the AdeB efflux pump and restores chlorhexidine effect on A. baumannii.
However, the addition of resveratrol increased chlorhexidine susceptibility with increased intracellular accumulation of ethidium bromide in A. baumannii indicating that resveratrol acts as an efflux pump inhibitor.
The combination of resveratrol and chlorhexidine resulted in strong synergistic and bactericidal activity against carbapenem-resistant A. baumannii.
PloS one  •  2020  |  View Paper