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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chlorhexidine
supplement:
Fluorides
Research Papers that Mention the Interaction
“The combination of CHX and F- rinses resulted in enamel mineral loss only slightly higher than that observed in "sound" enamel and clearly less than with F- rinses alone.”
Effect of a combined chlorhexidine and NaF mouthrinse: an in vivo human caries model study.“The results after 1 year showed that chlorhexidine induced less stain when applied together with fluoride than when applied alone.”
“ Chlorhexidine and CPP-ACP may be more effective than a placebo in managing caries in primary dentition, but their effectiveness is borderline when compared with fluoride.”
“Chemical control of plaque using chlorhexidine is indicated for patients at high microbiological risk; it is more effective at controlling caries when used in combination with fluorides.”
“BACKGROUND The side effects of chlorhexidine (CHX) have stimulated the search for alternative antiplaque agents such as amine fluoride/stannous fluoride (ASF) and essential oils (EO).”
“Based on the published reviews, it was concluded that chlorhexidine rinses, gels and varnishes or combinations of these items with fluoride have variable effects.”
“The additional use of chlorhexidine or toothpaste with a high fluoride concentration (which has been demonstrated to have an inhibitive effect) is rarely prescribed.”
“It is necessary for cases of high caries risk to use chlorhexidine in conjunction with fluoride to achieve caries arrest and remineralization of adjacent areas of the affected teeth.”
“For patients with extremely low saliva flow rates, the combined chlorhexidine and fluoride method may be required.”
“Combinations of chlorhexidine with fluoride may be even more effective.”
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