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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chlorhexidine
supplement:
Eucalyptus Oil
Research Papers that Mention the Interaction
“ConclusionThe delivery of CHG into the epidermis and dermis can be enhanced by combination with EO , which in turn may improve biocide contact with additional microorganisms present in the skin, thereby enhancing antisepsis.”
“The concentration of CHG (μg/mg of skin) was determined to a skin depth of 1500 μm by high performance liquid chromatography (HPLC).ResultsThe 2% (w/v) CHG penetration into the lower layers of skin was significantly enhanced in the presence of EO.”
Enhanced chlorhexidine skin penetration with eucalyptus oil“Antibacterial and in vivo biofilm preventive efficacies of all the concentrations of eucalyptus oil were significantly (P < 0.001) higher than that of M. spicata oil and chlorhexidine.”
“Furthermore, the combination of EO with CHG demonstrated synergistic activity against S. epidermidis biofilm with a fractional inhibitory concentration index of <0.5.”
Antimicrobial efficacy of chlorhexidine digluconate alone and in combination with eucalyptus oil, tea tree oil and thymol against planktonic and biofilm cultures of Staphylococcus epidermidis.
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