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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chlorhexidine
supplement:
Edetic Acid
Research Papers that Mention the Interaction
“Final irrigation with CHX following irrigation with 17% EDTA or 5% EDTA and 2.5% NaOCl (groups 4 and 5) significantly increased the fracture resistance of roots (P < 0.05).”
Effect of final irrigation procedures on fracture resistance of root filled teeth: an ex vivo study“It was concluded that the application of 2% CX followed by the application of 17% EDTA resulted in increasing the bond strength of the self-etching adhesive system to dentine, when compared with the results obtained for the other tested groups.”
“Escherichia coli, however, was susceptible to a second instillation provided that it was performed within 12 h. Supplementing chlorhexidine with EDTA and TRIS potentiated its activity against E. coli.”
“It has been known for some time that the chelating agent ethylenediamine-tetraacetic acid (E.D.T.A.) enhances the effects of various antibacterial agents, including polymyxin B and chlorhexidine diacetate, against Ps.”
“ Chlorhexidine showed a marked concentration‐dependent reduction of FAC.Even small amounts of SmearOFF or EDTA cause a significant loss of FAC.”
Free Active Chlorine in Sodium Hypochlorite Solutions Admixed with Octenidine, SmearOFF, Chlorhexidine, and EDTA“The combination of chlorhexidine and EDTA had excellent synergy against P. aeruginosa.”
“Pretreating biofilms with EDTA promoted the accumulation of CHX in all cells.”
“The precipitates formed in the reaction of CHX with EDTA , saline solution, and ethanol were associated with acid-base reactions, salting-out process, and lower solubility, respectively.”
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