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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chlordiazepoxide
supplement:
Yohimbine
Research Papers that Mention the Interaction
“In addition, we found that pre-treatment with the behaviourally active doses of the benzodiazepine (BDZ) anxiolytic chlordiazepoxide (CDE, Librium: BDZ very similar to diazepam) and of the non-BDZ buspirone counteract the effects of YOH on catecholamines release and cell firing.”
Anxiolytics antagonize yohimbine-induced central noradrenergic activity: A concomitant in vivo voltammetry–electrophysiology model of anxiety“A partial antagonism of yohimbine cueing was also obtained with meprobamate, phenobarbital, chlordiazepoxide , and clonazepam.”
“The benzodiazepine chlordiazepoxide (5-10 mg/kg), which reduces the activity of noradrenergic neurones, antagonized the effects of yohimbine less effectively.”
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