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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chloramphenicol
supplement:
Edetic Acid
Research Papers that Mention the Interaction
“Marked inhibition of transfer of resistance to chloramphenicol in the presence of the main proteins and EDTA was found.”
[Effect of biologically active compounds on the resistance of bacteria to antibiotics].“The repair of single strand breaks proceeds by two separate mechanisms, one of which is resistant to CAP , proceeds without thymidine incorporation, and is inhibited by EDTA.”
“Weiser, Asscher and Wim-penny4 reported that EDTA increases the sensitivity of certain organisms resistant to penicillin, ampicillin, chlor-amphenicol and tetracycline presumably by overcoming their permeability barrier to these antimicrobials.”
“Abstract The disodium salt of ethylenediamine-tetra-acetic acid (E.D.T.A., edetic ) enhances the effect of penicillin G, ampicillin, tetracycline, and chloramphenicol on a resistant strain of Pseudomonas œruginosa.”
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