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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chloramphenicol
supplement:
Cocaine
Research Papers that Mention the Interaction
“Exposure of slices from phenobarbital-induced Lewis rats to CAP concentrations ranging from 100 to 500 microM resulted in a concentration-dependent decrease in P450 2B activity and a corresponding decrease in cytotoxicity as measured by K+ loss following exposure to 1 mM cocaine.”
Inactivation of cytochromes P450 2B protects against cocaine-mediated toxicity in rat liver slices.“Indomethacin (5 microM), SKF-525A, and chloramphenicol also failed to block vasoconstriction induced by cocaine.”
“Troleandomycin, chloramphenicol and erythromycin all potentiated the locomotor activating effects of cocaine , although the effect was only statistically significant for the first two drugs.”
Certain clinically‐utilized antibiotics enhance the behavioural effects of cocaine
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