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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Chloramphenicol and Ascorbate

supplement:

Ascorbate

Research Papers that Mention the Interaction

Combinations of zinc ascorbate with clindamycin, erythromycin, and chloramphenicol showed an additive effect, and zinc ascorbate alone effectively inhibited the growth of all P. acnes including clindamycin-resistant strains.
Clinical, cosmetic and investigational dermatology  •  2011  |  View Paper
Chloramphenicol which inhibits protein synthesis, anaerobic medium and EDTA, which prevent ascorbate oxidation, and exogenous catalase, which removes hydrogen peroxide from the medium, all prevented the increase in catalase in response to ascorbate.
Biochemical and biophysical research communications  •  1981  |  View Paper